Altmeyer 2004

Methods	Individual randomised controlled trials
Participants	Diagnosis (Dx): seborrhoeic dermatitis of the scalp (physician diagnosis implied from text) Exclude if patient has psoriasis, atopic dermatitis, long hair, pregnancy and others (see Table 1, page 10)
Interventions	Intervention (Int): ciclopirox 1% shampoo applied twice weekly to scalp for 28 days (n = 51) Control: Vehicle shampoo applied similarly (n = 51) Ciclopirox 0.3% shampoo applied similarly (n = 51) Ciclopirox 0.1% shampoo applied similarly (n = 51) We combined second and third control groups into a single meta-analysis
Outcomes	Total clearance
Notes	Country: Germany; conflict of interest (COI): none This study randomly assigned 203 participants to 4 groups, but the number of participants in each group is not given. We therefore assumed that they were equally shared among the groups. We assigned a total of 50 to the intervention (ciclopirox 1%) group and 51 to each of the control groups
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"... were randomised into four parallel groups"
Allocation concealment (selection bias)	Unclear risk	Not reported
Baseline comparable?	Low risk	Duration and sex similar, but age not reported
Patient blinded?	Unclear risk	"... double-blind ..."
Provider blinded?	Unclear risk	"... double-blind ..."
Outcome assessor blinded?	Unclear risk	"... double-blind ..."
Co-interventions avoided?	Low risk	"... concomitant medications were not allowed"
Compliance acceptable?	Unclear risk	Not reported
Drop-out acceptable?	Unclear risk	Not reported
Selective outcome reporting acceptable?	Low risk	All proposed outcomes were reported
ITT?	Unclear risk	Unclear from analysis