Elewski 2007

Methods	Individual randomised controlled trials
Participants	Diagnosis: mild to moderate SD of the scalp, body and face (physician diagnosis implied in text). Participants must be immunocompetent, older than 11 years of age Exclusion criteria: other skin conditions, allergies, use of investigational therapy within 8 weeks before the study
Interventions	Intervention: keto 2% foam applied to the scalp and face twice daily for 4 weeks (n = 427) Control 1: vehicle foam applied similarly (n = 105) Control 2: 2% keto cream applied similarly (n = 420)
Outcomes	Overall clearance, symptom clearance
Notes	Country: USA Conflict of interest: study conducted by employees and consultants to Stieffel Laboratories Multi-centre study
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"... randomized ... study"
Allocation concealment (selection bias)	Unclear risk	Not reported
Baseline comparable?	Low risk	Refer to Table 1
Patient blinded?	Unclear risk	"... double-blinded study"
Provider blinded?	Unclear risk	"... double-blinded study"
Outcome assessor blinded?	Unclear risk	"... double-blinded study"
Co-interventions avoided?	Unclear risk	Not reported
Compliance acceptable?	Unclear risk	Not reported
Drop-out acceptable?	Low risk	"... low drop-out rate with 96% ... completing ..."
Selective outcome reporting acceptable?	Unclear risk	Not reported
ITT?	Low risk	"The ITT population included all 1162 ..."