Go 1992

Methods	Individual randomised controlled trials
Participants	Dx: dandruff Exclusion criteria: pregnancy, younger than 18 years of age, not using topical steroids in the past 2 weeks
Interventions	Intervention: 1% keto - shampoo applied 2× weekly for 4 weeks (n = 88) Control: vehicle shampoo applied similarly (n = 88)
Outcomes	Complete clearance
Notes	Country: The Netherlands COI: none declared
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"Patients were randomly allocated to either .."
Allocation concealment (selection bias)	Unclear risk	Not stated
Baseline comparable?	Low risk	"At the start the 2 treatment showed no significant difference in history of dandruff and severity?"
Patient blinded?	Unclear risk	''double blind study..''
Provider blinded?	Unclear risk	"double blind study..''
Outcome assessor blinded?	Unclear risk	"double blind study..''
Co-interventions avoided?	Low risk	"The patient who used a corticosteroid concomitantly was removed from the efficacy analysis"
Compliance acceptable?	Low risk	"... one subject stopped treatment after one week because of an adverse effect"
Drop-out acceptable?	Unclear risk	"Only one patient in the KTZ group stopped treatment due to greasy ..."
Selective outcome reporting acceptable?	Low risk	All outcomes were reported
ITT?	Unclear risk	Not stated