Satriano 1987

Methods	Individual randomised controlled trials
Participants	Diagnosis: SebDerm of duration over 5 years Sex: M (28/40); age: 29.3 years on average; duration: 100% longer than 5 years
Interventions	Int: ketoconazole cream 2% applied facially 2× daily for 28 days; ketoconazole 1% shampoo applied to scalp 2× weekly for 28 days (n = 20) Placebo: not specified but applied similarly (n = 20)
Outcomes	Symptom severity score for erythema, desquamation and pruritus at 4 weeks
Notes	Country: Italy
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"... in two randomised groups"
Allocation concealment (selection bias)	Unclear risk	Not reported
Baseline comparable?	Unclear risk	Not reported
Patient blinded?	Unclear risk	Double-blind
Provider blinded?	Unclear risk	Double-blind
Outcome assessor blinded?	Unclear risk	Double-blind
Co-interventions avoided?	Unclear risk	Not reported
Compliance acceptable?	Unclear risk	Not reported
Drop-out acceptable?	Unclear risk	Not reported
Selective outcome reporting acceptable?	High risk	Global evaluation reported only for open part of trial
ITT?	Unclear risk	Not reported