Sei 2011

Methods	Individual randomised controlled trial
Participants	Diagnosis: dandruff (n = 40), implied physician diagnosis Male: Int 12/17, Control 12/18; age: Int 43 ± 25, Control 46 ± 22; severity: moderate: Int 15/19, Control 12/16 Excluded: patients taking antifungal argent orally or topically on their head and/or patients who did not use rinse in washing their hair
Interventions	Int: miconazole nitrate: Rinse together with miconazole nitrate shampoo (n = 17); mean use: 5.8 ± 1.8 days per week during 4 weeks (n = 19) Control: placebo rinse with miconazole nitrate shampoo (n = 14); mean use 5.9 ± 2.4 days per week during 4 weeks (n = 18)
Outcomes	Dandruff eliminated after 4 weeks; itching eliminated after 4 weeks
Notes	Country: Japan COI: not reported Translation by native speaker
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"used block randomisation with a block size of four"
Allocation concealment (selection bias)	Unclear risk	Not reported
Baseline comparable?	Low risk	See participant characteristics
Patient blinded?	Unclear risk	Not reported
Provider blinded?	Unclear risk	Not reported
Outcome assessor blinded?	Unclear risk	Not reported
Co-interventions avoided?	Unclear risk	Not reported
Compliance acceptable?	Low risk	Yes, used shampoo 5 out of 7 days on average
Drop-out acceptable?	Low risk	20%
Selective outcome reporting acceptable?	Unclear risk	Not clear if all outcomes reported
ITT?	Unclear risk	No imputation for loss to follow-up