Stratigos 1988

Methods	Individual randomised controlled trials
Participants	Dx: SD of the scalp, face and trunk Male (36/72); age: 33 years on average; duration: 16 months on average
Interventions	Intervention: 2% keto cream applied once daily to affected area for 1 month (n = 29) Control: 1% hydrocortisone cream applied similarly (n = 34)
Outcomes	Total clearance and symptom scores for erythema, scaling and pruritus
Notes	Country: Greece, Austria and Belgium Sponsored by Janssen; adverse effects: dryness and skin tension - ketoconazole (1), hydrocortisone (2)
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"assigned ... in a randomized fashion"
Allocation concealment (selection bias)	Unclear risk	Not reported
Baseline comparable?	Low risk	Age, sex and severity
Patient blinded?	Unclear risk	"... double-blind ..."
Provider blinded?	Unclear risk	"... double-blind ..."
Outcome assessor blinded?	Unclear risk	"... double-blind ..."
Co-interventions avoided?	Low risk	Not allowed
Compliance acceptable?	Unclear risk	Not reported
Drop-out acceptable?	Low risk	Not reported
Selective outcome reporting acceptable?	Low risk	All outcomes reported
ITT?	Low risk	Not reported