Table 4.

P -values calculated by t tests from logarithmic ratios between treated and control samples

	C2-1d	C5-1d	C10-1d	C5-10d	C10-42d
P -values	vs	vs	vs	vs	vs
	T2-1d	T5-1d	T10-1d	T5-10d	T10-42d
Control < treated	6.9×10−4	7.4×10−8	1.0	0.22	0.03
Control > treated	1.0	1.0	2.35×10−8	0.78	0.97

Smaller P-values indicate that the difference in mean logarithmic ratio is more significant in the selected 59 mRNAs than that in the other mRNAs. For descriptions of each experimental condition, see the caption for Figure 9. For more methodological detail, see Additional file 2.