Table 5.

Summary of studies with association between heart disease and genes selected by CPCAFE

Gene	RefSeq mRNA	miRNAs	Heart disease association ( P -values from the Gendooserver)
Fabp3	NM_010174	miR-709	Cardiomegaly (0.031)
Cox4i1	NM_009941	miR-709	Cardiac output, low (5×10−4)
Atp5g1	NM_001161419	miR-29a/b-3p,	Cardiomyopathies (1.5×10−3)
		miR-16
Cox6a2	NM_009943	miR-23a/b-3p	Heart disease (1.3×10−3); Cardiomyopathies (2.3×10−3);Heart failure (5.0×10−3)
Aldoa	NM_001177307	miR-16	Cardiomyopathy, dilated (2.0×10−3)
Cox5a	NM_007747	miR-26a-5p	Cardiomyopathies (5.4×10−3); Myocardial ischemia(7.4×10−4)
Myl2	NM_010861	miR-1983	Heart defects, congenital (4.9×10−48); Cardiomyopathy, dilated (5.2×10−21); Cardiomegaly (1.1×10−17); Heart failure (2.1×10−9)
Myl3	NM_010859	miR-691	Heart defects, congenital (1.1×10−7); Cardiomegaly(1.2×10−4); Myocardial infarction (2.4×10−4); Heart septal defects, ventricular (6.9×10−4)
Tcap	NM_011540	miR-207	Cardiomyopathy, dilated (1.1×10−8); Cardiomyopathy, hypertrophic (1.7×10−3); Heart defects, congenital(6.0×10−3); Heart failure (1.2×10−2)