Table 3.
Baseline demographic and clinical characteristics (preoperative, intraoperative, and postoperative) of patients
| PaO 2 /FIO 2 | PaO 2 /FIO 2 | PaO 2 /FIO 2 | p value | |
|---|---|---|---|---|
| ratio > 241 | ratio 202-241 | ratio < 202 | ||
| (n = 2195) | (n = 257) | (n = 249) | ||
| Preoperative data | ||||
| Age | 65.3 (11.1) | 66.1 (9.6) | 66.0 (10.2) | 0.392 |
| BMI (kg∙m-2) | 27.9 (8.5) | 28.8 (4.2) | 29.7 (17.5) | 0.09 |
| Gender (% male) | 60.1 | 73.5 | 72.7 | < 0.001 |
| HBP (%) | 61.8 | 67.7 | 66.7 | <0.001 |
| IDDM (%) | 8.2 | 9.3 | 8.0 | 0.867 |
| NIDDM (%) | 17.5 | 17.9 | 18.1 | 0.748 |
| DLP (%) | 51.2 | 56.4 | 47.8 | 0.354 |
| Smokers (%) | 19.8 | 28.4 | 26.5 | <0.001 |
| Vasculopathy (%) | 8.4 | 8.9 | 9.6 | 0.947 |
| COPD (%) | 9.9 | 17.5 | 21.7 | <0.001 |
| CRF (%) | 4.1 | 5.1 | 10.4 | <0.001 |
| Ejection fraction (%) | 60.7 (11.5) | 58.7 (13.0) | 60.0 (11.9) | 0.06 |
| Preoperative haematocrit (%) | 39.5 (4.9) | 40.5 (5.0) | 38.8 (6.0) | <0.001 |
| Preoperative platelets (x106/L) | 216423 (67126) | 213470 (60195) | 219409 (79665) | 0.615 |
| Preoperative creatinine (μmol/l) | 91.8 (48.5) | 94.6 (37.1) | 107.9 (80.8) | <0.001 |
| Parsonnet | 10.8 (6.4) | 11.5 (8.0) | 13.8 (9.9) | <0.001 |
| EuroSCORE | 5.2 (2.8) | 5.5 (3.2) | 6.2 (3.6) | 0.006 |
| Surgical group | ||||
| CABG (%) | 28.6 | 35.8 | 31.1 | 0.145 |
| Valve (%) | 62.7 | 55.3 | 60.7 | 0.145 |
| CABG + Valve (%) | 8.7 | 8.9 | 8.2 | 0.145 |
| CPB time (min) | 109.9 (36.4) | 115.1 (37.6) | 118.6 (40.7) | <0.001 |
| Cross-clamping time (min) | 71.9 (26.6) | 73.2 (24.6) | 76.0 (29.7) | 0.07 |
| Main Postoperative data | ||||
| SAPS II | 22.8 (8.9) | 26.4 (9.0) | 29.3 (10.4) | <0.001 |
| APACHE II | 11.7 (4.2) | 13.0 (4.8) | 14.7 (5.4) | <0.001 |
| APACHE III | 47.6 (16.2) | 52.8 (18.5) | 60.8 (20.7) | <0.001 |
| Blood lactate at ICU admission (mmol/L) | 2.3 (5.6) | 2.3 (1.2) | 2.4 (1.4) | 0.960 |
| TnI at ICU admission (μg/L) | 6.5 (7.0) | 7.0 (11.8) | 9.4 (25.5) | <0.001 |
| Need for blood products (units) | 1.8 (2.5) | 1.4 (2.8) | 1.9 (3.1) | 0.17 |
| ICU stay (days) | 6.4 (9.2) | 8.48 (11.6) | 12.5 (15.1) | <0.001 |
| Hospital stay (days) | 23.6 (19.5) | 24.7 (18.0) | 31.7 (23.0) | <0.001 |
| In-ICU exitus (%) | 2.6 | 4.7 | 8.4 | < 0.001 |
| In-hospital exitus (%) | 4 | 6.2 | 11.2 | <0.001 |
PaO2/FiO2 Arterial partial pressure of O2 and fraction of inspired oxygen ratio, HBP High blood pressure, IDDM Insulin-dependent diabetes mellitus, NIDDM, Non-insulin-dependent diabetes mellitus, DLP Dyslipidaemia, COPD, Chronic obstructive pulmonary disease, CRF Chronic renal failure, BMI Body Mass Index, EuroSCORE European system for cardiac operative risk evaluation, SAPS Simplified Acute Physiology Score, APACHE Acute Physiology and Chronic Health Evaluation, CPB Cardiopulmonary bypass, CABG Coronary artery bypass graft, TnI Troponin I, Data expressed as mean (SD).