Table 2.

Evaluation of the interaction between rs73885319 and HDLC on eGFR among African Americans by study

	rs73885319		logHDL		rs73885319 × logHDL
	β (SE)	P-value	β (SE)	P-value	β (SE)	P-value
HUFS, NHAAN, and ARIC combined	−1.32 (1.26)	0.30	4.69 (2.08)	0.02	−37.42 (9.74)	0.0001
HUFS	0.51 (2.45)	0.83	−0.12 (4.30)	0.98	−52.12 (18.55)	0.005
NHAAN	−3.73 (2.34)	0.11	7.09 (6.11)	0.25	−50.35 (18.18)	0.006
ARIC	−1.84 (2.06)	0.37	8.03 (2.24)	0.0003	−10.30 (17.03)	0.55
ARIC (≤55 years)	−2.17 (2.59)	0.40	7.69 (2.88)	0.008	−29.78 (21.78)	0.17
HUFS, NHAAN, and ARIC combined (≤55 years)	−1.24 (1.50)	0.41	5.31 (2.54)	0.04	−49.47 (11.44)	0.00002

Results are from a model of eGFR as predicted by rs73885319 × HDLC, adjusted for rs73885319, HDLC, age, BMI, sex, genome-wide proportion of African ancestry, study (where combined), and the random effect of family