Table 2.
Characteristics of SCD patients with chronic kidney disease
| Variable | Hb Genotype | ||
|---|---|---|---|
| SS | SC | P-value | |
| (n = 58) | (n = 18) | ||
| Age (years) | 25.10 ± 9.73 | 35.33 ± 14.82 | <0.001 |
| Gender | |||
| Male | 32 (55.2) | 4 (22.2) | 0.084 |
| Female | 26 (44.8) | 14 (77.8) | |
| Age group n (%) | |||
| <10 | 2 (3.4) | 0 (0.0) | 0.373 |
| 10-19. | 20 (34.5) | 2 (11.1) | |
| 20-29 | 22 (37.9) | 6 (33.3) | |
| 30-39 | 8 (13.8) | 4 (22.2) | |
| ≥40 | 6 (10.3) | 6 (33.3) | |
| Blood pressure (mmHg) | |||
| SBP | 109.21 ± 7.04 | 115.78 ± 7.45 | 0.005 |
| DBP | 64.93 ± 7.64 | 74.22 ± 8.69 | 0.011 |
| BMI (Kg/m2) | 17.75 ± 3.32 | 19.20 ± 4.35 | 0.599 |
| BMI n (%) | |||
| Underweight | 36 (62.1) | 12 (66.7) | 0.018 |
| Normal | 22 (37.9) | 2 (11.1) | |
| Overweight | 0 (0.0) | 4 (22.2) | |
| Haematological profile | |||
| WBC x 103/mm3 | 11.43 ± 3.07 | 8.41 ± 3.82 | 0.020 |
| RBC x106/mm3 | 2.93 ± 0.86 | 4.15 ± 1.02 | 0.001 |
| HGB (g/dl) | 8.35 ± 1.60 | 10.83 ± 2.56 | 0.001 |
| HCT (%) | 29.74 ± 8.02 | 29.91 ± 7.83 | 0.989 |
| PLT x 103/mm3 | 348.1 ± 140.5 | 205.9 ± 84.42 | 0.007 |
P <0.05 is significant, SBP = Systolic Blood Pressure, DBP = Diastolic Blood Pressure, BMI = Body Mass Index, eGFR = estimated Glomerular Filtration Rate, WBC = White Blood Cell, RBC = Red Blood Cell, HGB/Hb = Haemoglobin, HCT = Haematocrit, PLT = Platelet