Table 4.
Association of MDM2-rs2279744 SNP with the clinicopathological data from lung cancer patients
| Characteristic | G/G (n = 231) | T/T + G/T (n = 769) | P-value | |
|---|---|---|---|---|
| Gender | Male | 141 | 466 | 0.965 |
| Female | 90 | 303 | ||
| Age (years) | <30 | 3 | 4 | 0.530 |
| 30–39 | 5 | 25 | ||
| 40–49 | 36 | 98 | ||
| 50–59 | 85 | 287 | ||
| 60–69 | 75 | 247 | ||
| ≥70 | 27 | 108 | ||
| BMI (kg/m2) | <18.5 | 8 | 56 | 0.101 |
| 18.5–24 | 130 | 402 | ||
| ≥24 | 93 | 311 | ||
| Histology types | Squamous cell | 35 | 106 | 0.946 |
| Adenocarcinoma | 48 | 128 | ||
| Small cell | 31 | 95 | ||
| Other carcinomas* | 15 | 42 | ||
*Including large cell, mixed cell carcinoma, or undifferentiated carcinoma. BMI, Body mass index; MDM2, mouse double minute-2; SNP, single nucleotide polymorphism.