Table 2.
Patient characteristics and comparison of RFS based on variables
| Variable | No. of patients | 5-year RFS (%) | P-value |
|---|---|---|---|
| Age | 0.540 | ||
| <65 | 42 | 33.3 | |
| ≥65 | 54 | 21.6 | |
| Gender | 0.961 | ||
| Male | 63 | 32.7 | |
| Female | 33 | 19.4 | |
| Smoking history | 0.445 | ||
| Yes | 63 | 26.2 | |
| No | 33 | 29.9 | |
| Extent of resection | 0.258 | ||
| Lobectomy | 82 | 29.1 | |
| Bilobectomy | 11 | 18.2 | |
| Pneumonectomy | 3 | 33.3 | |
| Tumour location | 0.103 | ||
| LUL | 22 | 38.6 | |
| LLL | 14 | 24.5 | |
| RUL | 26 | 29.4 | |
| RML | 7 | 42.9 | |
| RLL | 27 | 17.9 | |
| Histology | 0.099 | ||
| Adenocarcinoma | 65 | 28.0 | |
| Others | 31 | 30.1 | |
| Adjuvant therapy | 0.126 | ||
| Chemotherapy | 46 | 32.9 | |
| Others | 50 | 21.8 | |
| pT stage | 0.061 | ||
| T1 | 13 | 44.9 | |
| T2 | 56 | 32.7 | |
| T3 | 23 | 16.8 | |
| T4 | 4 | 0 | |
| Distribution of metastatic N2 | 0.006 | ||
| Regional | 65 | 35.0 | |
| Non-regional | 31 | 11.8 | |
| Highest MLN status | 0.161 | ||
| Negative | 47 | 38.4 | |
| Positive | 49 | 15.8 | |
| Subcarinal zone status | 0.073 | ||
| Negative | 51 | 31.5 | |
| Positive | 45 | 24.2 | |
| Skip N2 metastasis | 0.434 | ||
| Yes | 37 | 29.5 | |
| No | 59 | 26.5 | |
| Clinical N status | 0.505 | ||
| cN0-1 | 60 | 29.5 | |
| cN2 | 36 | 23.8 | |
| No. of metastatic N2 lymph nodes | 0.000 | ||
| ≤3 | 62 | 40.0 | |
| >3 | 34 | 4.7 | |
| N2 station involved | 0.002 | ||
| Single | 51 | 43.8 | |
| Multiple | 45 | 11.3 | |
| N2 zone involved | 0.009 | ||
| Single | 56 | 40.0 | |
| Multiple | 40 | 12.5 |
LLL, left lower lobe; LUL, left upper lobe; MLN, mediastinal lymph node; RFS, recurrence-free survival; RLL, right lower lobe; RML, right middle lobe; RUL, right upper lobe.