Table 2.
Univariate analysis for recurrence of 95 pN1 ESCC patients undergoing radical esophagectomy with lymphadenectomy
| Variables | n. | Recurrence [n. (%)] | P-value |
|---|---|---|---|
| Gender (M/F) | 79/16 | 43(54.4)/9(59.2) | 0.168 |
| Age (years)(≥60/<60) | 62/33 | 35(56.5)/17(51.5) | 0.134 |
| Tumor location | 0.182 | ||
| Upper | 9 | 5(55.6) | |
| Middle | 63 | 37(58.7) | |
| Lower | 23 | 10(43.5) | |
| Grade of differentiation | 0.138 | ||
| Well (G1) | 9 | 4(44.4) | |
| Moderately (G2) | 38 | 22(57.9) | |
| Poorly (G3) | 48 | 26(54.2) | |
| T status | 0.003 | ||
| T1b | 6 | 1(16.7) | |
| T2 | 17 | 5(29.4) | |
| T3 | 60 | 39(65.0) | |
| T4a | 12 | 7(58.3) | |
| Positive lymph nodes number (1/2) | 73/23 | 34(47.2)/18(78.3) | 0.041 |
| Positive lymph nodes stations (1/2) | 76/19 | 34(44.7)/18(94.7) | 0.001 |
| Positive lymph nodes fields (1/2) | 87/8 | 44(50.6)/8(100.0) | 0.000 |
| Pathologic stage | 0.012 | ||
| IIB | 23 | 6(26.1) | |
| IIIA | 60 | 39(65.0) | |
| IIIC | 12 | 7(58.3) | |
| Lymphadenectomy (2-field/3-field) | 76/19 | 43(56.6)/9(47.4) | 0.174 |
| Intramural metastasis (yes/no) | 5/90 | 5(100.0)/47(52.2) | 0.000 |
| Lymph-vascular invasion (yes/no) | 7/88 | 6(85.7)/46(52.3) | 0.019 |
| Postoperative adjuvant chemotherapy (yes/no) | 69/26 | 33(47.8)/19(73.1) | 0.036 |
ESCC, esophageal squamous cell carcinoma.