FIGURE 4.

Bursts of NMDA sEPSCs during postnatal development. (A) Voltage-clamp recordings of NMDA sEPSCs from a P8 SNc TH-GFP neuron in the continuous presence of gabazine (5 μM) and NBQX (10 μM) at V_H = +40 mV. The stars (black and blue) indicate bursts of NMDA sEPSCs. The other events are single events either isolated or in trains. The burst indicated by a blue star is shown in the inset at a more rapid time base. (B) Quantification and statistical comparison of the number of bursts per cell per 3 min from P4–P10 and P30+ SNc DA neurons. In this and subsequent figures, when indicated, ^∗P < 0.05 and ^∗∗P < 0.01.