Figure 1.

Schematic of the human retina. The major layers of the retina are shown schematically: NFL, nerve fiber layer; GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium; BM, Bruch's membrane; and CV, choroidal vasculature. The photoreceptors, retinal pigment epithelium, and choroidal vasculature (indicated by red bracket on right of schematic) are the cell types that are most commonly affected by inherited retinal diseases.