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. 2015 Jun;5(6):a024158. doi: 10.1101/cshperspect.a024158

Table 1.

Recommended therapy for cryptococcal meningoencephalitis in HIV

Phase 0–2 wk 2–10 wk 10 wk–1 yr
Induction Amphotericin 0.7–1.0 mg/kg/d + 5FC 100 mg/kg/d Alternative regimens: AmBd + fluconazole 800–1200 mg/d Liposomal AmB 3–4 mg/kg/d; fluconazole 1200 mg/d + 5FC
Consolidation Fluconazole 400 mg/d
Maintenance Fluconazole 200 mg/d for 6–12 mo or until CD4 >100 and HIV viral load undetectable on ART