Table 2. Quantification of transduced motor neurons throughout the spinal cord.
| Animal # | ROA | Promoter |
Percent GFP+ motor neuronsa |
||
|---|---|---|---|---|---|
| Cervical | Thoracic | Lumbar | |||
| 17 | CM | CMV | ND | 10.7 ± 11.4 | 14.5 ± 17.6 |
| 18 | CM | CB | 0 ± 0 | 8.4 ± 2.3 | 20.3 ± 4.9 |
| 20 | CM | CB | 0.3 ± 0.6 | 25.1 ± 17.0 | 19.3 ± 11.0 |
| 21 | CM | CB | 1.5 ± 2.1 | 48.0 ± 15.6 | 38.2 ± 23.4 |
| 04 | L | CB | 0.3 ± 0.6 | 0 ± 0 | 0.6 ± 1.3 |
| 05 | L | CB | 0 ± 0 | 1.7 ± 2.9 | 2.6 ± 5.2 |
| 49 | IV | CMV | 0 ± 0 | 7.7 ± 10.5 | 0.2 ± 0.5 |
CM, cisterna magna; IV, intravenous; L, lumbar injection; ROA, route of administration.
a
Mean ± SD in four fields.