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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: J Pharm Sci. 2015 Mar 5;104(5):1575–1591. doi: 10.1002/jps.24379

Figure 4.

Figure 4

Determination of relative standard deviation percentage (RSD %) of MFI particle count and determination of enrichment factors for FACS separated samples of mAb2 particles. (A) Representative FACS sorted sample of stir-induced aggregated mAb2, obtained as outlined in Figure 3 and having undergone two freeze-thaw cycles, was used for repeat MFI testing to determine RSD % as a function of particle size bins (N=9 with the error bars representing one standard deviation), and (B) enrichment analysis of FACS sorted samples (Sort I, II, III, IV) after undergoing two freeze-thaw cycles. Data are an average of three separate experiments (N=3) with the error bars representing one standard deviation.