Table 3.
Association between parental history and asthma risk in the children, adjusting for obesity status
| Type of indicator | Father (10.53 million)
|
Mother (13.12 million)
|
||
|---|---|---|---|---|
| Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | |
| Father’s or mother’s asthma history available | ||||
| Binary indicator | 3.012 (1.124, 8.074) | 0.0292 | 4.372 (1.699, 11.250) | 0.0029 |
| Log-rank risk score | 1.227 (0.993, 1.517) | 0.0579 | 1.267 (1.074, 1.494) | 0.0058 |
| Weighted log-rank risk score | 1.931 (1.062, 3.509) | 0.0316 | 2.955 (1.935, 4.515) | 4.8×10−6 |
|
Father (9.04 million)
|
Mother (9.04 million)
|
|||
| Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | |
|
| ||||
| Father’s and mother’s asthma history available | ||||
| Binary indicator | 2.165 (0.691, 6.788) | 0.1805 | 3.714 (1.189, 11.600) | 0.0249 |
| Log-rank risk score | 1.215 (0.976, 1.512) | 0.0801 | 1.373 (1.113, 1.694) | 0.0038 |
| Weighted log-rank risk score | 1.761 (0.929, 3.339) | 0.0815 | 3.210 (1.863, 5.533) | 0.0001 |