Table 1.

Influenza virus vaccines for the United States of America 2013–2014 season ^a

Seasonal influenza vaccines	Type/abbrev.	# Antigens	Route of administration	Manufacturer	Age range	Adjuvant
Afluria	Inactivated/IIV3b	Trivalent	Intramuscular	CSL Limited	5 ≥	None
FluLaval	Inactivated/IIV3b	Trivalent	Intramuscular	GlaxoSmithKline	18 ≥	None
Fluarix	Inactivated/IIV3b	Trivalent	Intramuscular	GlaxoSmithKline	3 ≥	None
	Inactivated/IIV4b	Quadrivalent	Intramuscular			None
Flublok	Recombinant/RIV3c	Trivalent	Intramuscular	Protein Sciences	18-49	None
Flucelvax	Cell Culture/ccIIV3b	Trivalent	Intramuscular	Novartis	18 ≥	None
FluMist	Live Attenuated/LAIV4d	Quadrivalent	Intranasal	Medimmune	2-49	None
Fluvirin	Inactivated	Trivalent	Intramuscular	Novartis	4 ≥	None
Fluzone	Inactivated/IIV3b	Trivalent	Intramuscular	Sanofi Pasteur	6 mo ≥e	None
	Inactivated/IIV4b	Quadrivalent	Intramuscular			None

^aU.S. Food and Drug Administration recommends that the trivalent-formulation influenza vaccines for the U.S. 2013–2014 influenza season contain the following: (1) A/California/7/2009 (H1N1)-like virus, (2) (H3N2) virus antigenically like the cell-propagated prototype virus A/Victoria/361/2011, and (3) B/Massachusetts/2/2012-like virus. For the quadrivalent-formulation influenza vaccines for the U.S. 2013–2014 influenza season contain the above three strains and the following additional B strain: (4) B/Brisbane/60/2008-like virus. ^bIIV refers to inactivated vaccines (egg and cell-culture based). Includes trivalent (IIV3) and quadrivalent (IIV4). ^cRIV refers to recombinant HA influenza vaccine. Trivalent (RIV3). ^dLAIV refers to Live Attenuated Influenza Vaccine. Quadrivalent (LAIV4). ^eDose dependent. Informations were found on web sites: http://www.emergency.cdc.gov/coca/ppt/2013/08_13_13_Immunizations.pdf, http://www.fda.gov/biologicsbloodvaccines/guidancecomplianceregulatoryinformation/post-marketactivities/lotreleases/ucm343828.htm (accessed on 4 September 2013).