Figure 4.
Reversible inhibition of BzATP-induced effects by AZD9056. Cytosensor measurements using HEK–hP2X7 cells and parental HEK293 cells in the presence and absence of 10 μmol/L AZD9056. After a wash-out period of 4 h, the cells were again stimulated with 50 μmol/L BzATP to assess regeneration and reactivation. Level of significance in the presence and absence of antagonist: *P < 0.05, n = 4.