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. 2015 Mar 25;3(2):e00132. doi: 10.1002/prp2.132

Figure 6.

Figure 6

Therapeutic activity of compound B toward the depression-like symptom in the TST. Mice were treated with CORT or vehicle for 21 days and subsequently with compound B (0.3 or 1.5 mg/kg) or vehicle for 7, 14, or 21 days (see protocol B in Fig.2). Then, the time immobilized in the TST was measured. The significance of the difference between the value of the CORT-treated group and that of the vehicle-treated group was determined by one-way ANOVA with Tukey's post hoc test, as *P < 0.05, **P < 0.01 (n = 6/group). Among the CORT-treated groups, significant differences from the value of the vehicle-treated group were also determined by one-way ANOVA with Tukey's test, as ##P < 0.01 (n = 6/group). TST, tail suspension test. ANOVA, analysis of variance.