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. 2015 Mar 31;3(2):e00129. doi: 10.1002/prp2.129

Figure 5.

Figure 5

UGE values in mice treated with a single dose of LP-925219. After DKO, S2 KO, S1 KO, and WT littermate mice received, by a single oral gavage at 8 am, either vehicle (Veh) or LP-925219 at a dose of (A) 1 mg/kg; (B) 10 mg/kg; or (C) 60 mg/kg, the mice were placed in metabolic cages and their urine was collected over the next 24 h and analyzed for total glucose. N = 5–11 mice/group. UGE < DKO UGE: *P < 0.05, **P < 0.01, ***P < 0.001; LP-925219 UGE > Veh UGE for the same group, ^^^P < 0.001. UGE, urinary glucose excretion.