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21 plant proteins are from the PlantCAZyme database, 12 animal proteins are from the CAZy database, 12 early eukaryotic proteins are from Table 1 and 29 early plant transcriptome-derived peptides are from S4 Table. Sequences were aligned using the MAFFT program. Phylogeny was inferred using RAxML program (see Methods). Complete species names are available in S3 Table and S4 Table.
