Table 1. Summary of transduction efficiencies.
Vectors |
|||||||
---|---|---|---|---|---|---|---|
AAV1 | AAV2 | AAV6 | AAV9 | Adenoviral | Lentiviral | ||
hESC | hES2C | 0a | 0a | 0a | 0a | ++ | + |
H9C | + | +++ | ++ | + | ++ | + | |
hiPSC | iPS31.3C | 0a | 0a | 0a | 0a | + | + |
iPS24.1C | 0a | 0a | +a | 0a | + | + | |
hESC-CMs | hES2C-CMs | ++ | +++ | +++ | + | +++ | ++ |
hiPSC-CMs | hiPSC-CMs | ++ | +++ | +++ | + | ++ | + |
Extensive cell death.