Table 2.

BRD9 potency of (2R,3S) derivatives by ITC.

	Compound	R	KD [nm]	ΔH [kcal mol−1]	TΔS [kcal mol−1]
	48	Boc	247	−9.88	1.17
	55	Bz	2000	−8.06	−0.764
	60	SO2iBu	99	−11.2	1.98
	64	CONHPh	1010	−6.52	−1.39

Bz=benzoyl.