Table 1. Q-FISH analysis of hepatocytes.
Chronic HBV infection | Controls | |||
---|---|---|---|---|
Mean | Standard deviation | Mean | Standard deviation | |
Number of telomeres per hepatocyte | 8.9 | 2.9 | 12.8 | 2.6 |
Mean of mean telomere length (Cy5 intensity) | 166 * | 119 | 465 | 159 |
Mean of maximum telomere lengths | 253 * | 183 | 721 | 229 |
Telomere area | 8.9 * | 1.3 | 10.2 | 1.5 |
Nuclear area in pixels (μm 2 ) | 4195 (48.5) | 524 | 4205 (48.6) | 496 |
* Values for patients with HBV differed significantly from controls (all p < 0.0001).