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. 2015 May 29;10(5):e0129192. doi: 10.1371/journal.pone.0129192

Table 4. Unadjusted odds ratios and multivariate adjusted odd ratios for development of albuminuria.

Hemoglobin, per 1.0 g/L increase
Men P Women P
Crude 0.95 (0.93–0.98) 0.0005 0.93 (0.89–0.96) < 0.0001
Model 1 0.94 (0.90–0.97) 0.0001 0.93 (0.88–0.97) 0.002
Model 2 0.93 (0.89–0.96) < 0.0001 0.94 (0.88–0.99) 0.013
Anemia, yes
Men P Women P
Crude 4.13 (1.82–9.1) 0.0005 6.97 (3.22–15.51) < 0.0001
Model 1 4.32 (1.60–11.62) 0.004 4.30 (1.54–12.62) 0.005
Model 2 4.78 (1.65–13.91) 0.004 4.62 (1.34–16.68) 0.013

Model 1 is adjusted for age, duration of diabetes, systolic blood pressure, hemoglobin, hemoglobin A1c, urinary albumin-creatinine ratio at baseline and the use of rennin-angiotensin system inhibitors. Model 2 includes all variables in Model 1 plus body mass index, total cholesterol, logarithm of triglycerides, uric acid, creatinine, smoking status, and the use of statin. Smoking status was defined as nonsmoker (= 0), previous smoker (= 1), or current smoker (= 2), and the use of rennin-angiotensin system inhibitors or statin was defined as without (= 0) or with (= 1).