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. 2015 May 29;10(5):e0128021. doi: 10.1371/journal.pone.0128021

Fig 5. Gene expression patterns in the alveolar bone healing after tooth extraction.

Fig 5

Molecular analysis of the gene expression patterns in the bone healing in the socket was comprised of an initial exploratory analysis by RealTimePCR array a pool comprised of samples from all the experimental time periods (0h, 7d, 14d, 21d). RealTimePCR array analysis was performed with the VIA7 system (Applied Biosystems, Warrington, UK) using a customized qPCRarray comprised of the major targets from the Osteogenesis, Inflammatory Cytokines & Receptors and Wound Healing panels of the PCRarrayRT2 Profiler (SABiosciences/QIAGEN). Results are depicted as the fold increase change (and the standard deviation) in mRNA expression from triplicate measurements in relation to the control samples and normalized by internal housekeeping genes (GAPDH, HPRT, β-actin). * indicate a statistically significant difference (p<0.05) between the experimental sample and the control.