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. 2015 May 29;10(5):e0128078. doi: 10.1371/journal.pone.0128078

Fig 3. hUCB-MSC-CM suppresses melanogenesis in an artificial human skin model.

Fig 3

(A-C) MelanoDerm tissues were incubated with either growth medium (Cont) or hUCB-MSC-CM for 20 days or resveratrol (RSV) for 18 days. Then the Melanoderm tissues were observed under a microscope (A) or analyzed by Masson-Fontana staining (B). The tissues were collected to determine the total melanin content (C). RSV was used as a positive control agent. Data represent standard error of the mean (S.E.M) from three independent experiments (n = 3, p<0.05)