Table 2. Table depicting the clinical signs displayed by the diabetic cats in the group with confirmed HS, compared to a group of cats newly diagnosed with primary diabetes mellitus (non-acromegalic).

n = 60	Number of diabetic cats with confirmed hypersomatotropism in which this was present (percentage) n = 60	Number of diabetic cats without HS in which this was present (percentage) n = 20	Fischer’s exact test result comparing the frequency clinical sign (p = value)
Polyuria	52 (87%)	15 (75%)	0.29
Polydipsia	52 (87%)	17 (85%)	1.0
Polyphagia	45 (75%)Of which extreme: 12 (20%)	11 (55%) Of which extreme: 0 (0%)	0.100.031
Weight loss	25 (42%)	12 (60%)	0.20
Weight gain	10 (17%)	0 (0%)	0.059
Respiratory stridor / ‘snoring’	23 (38%)	2 (10%)	0.025
CNS signs (excluding lethargy)	1 (1.7%)	0 (0%)	1.0
Lethargy	15 (25%)	7 (35%)	0.40
Stiffness / mobility problems	6 (10%)	2 (10%)	1.0
Abdominal organomegaly (renomegaly and/or hepatomegaly	24 (40%)	5 (25%)	0.29
Prognathia inferior (Fig 4)	11 (18%)	2 (10%)	0.50
Clubbed paw appearance (Fig 5)	8 (13%)	0 (0%)	0.19
Broad facial features (Fig 6)	22 (37%)	0 (0%)	<0.001
Heart murmur	11 (18%)	4 (20%)	1.0
Plantegrade stance	2 (3%)	2 (10%)	0.26

In bold: significant p-value, not corrected for multiple comparisons; in bold and underlined: significant p-value after Bonferroni post-hoc correction for multiple comparisons.