Table 1.
Characteristic | CTEPH patients (n = 259) | Control patients (n = 259) | P |
---|---|---|---|
Age, years | 58.3 ± 10.6 | 58.3 ± 10.8 | 0.98 |
Sex | |||
Male | 130 (50.2) | 130 (50.2) | NA |
Female | 129 (49.8) | 129 (49.8) | |
Race | |||
White | 196 (75.7) | 202 (78.0) | |
African American | 46 (17.8) | 21 (8.1) | 0.001 |
Asian | 6 (2.3) | 17 (6.6) | |
Unknown | 11 (4.2) | 19 (7.3) | |
BMI | 30.8 ± 7.1 | 29.5 ± 7.3 | 0.04 |
WHO functional class | |||
1 | 5 (1.9) | ||
2 | 47 (18.1) | NA | NA |
3 | 181 (69.9) | ||
4 | 26 (10.0) | ||
Comorbidities | |||
Diabetes | 56 (21.6) | 82 (31.7) | 0.01 |
Hypertension | 109 (42.1) | 170 (65.6) | <0.001 |
Hyperlipidemia | 64 (24.7) | 136 (52.5) | <0.001 |
Coronary artery disease | 10 (3.9) | 0 (0.0) | 0.001 |
Chronic kidney disease | 33 (12.7) | 34 (13.1) | 0.92 |
COPD | 23 (8.9) | 35 (13.5) | 0.09 |
Asthma | 23 (8.9) | 19 (7.3) | 0.52 |
Smoking history | |||
Never smoker | 143 (55.2) | 131 (50.6) | |
Former smoker | 89 (34.4) | 91 (35.1) | |
Current smoker | 21 (8.1) | 30 (11.6) | |
Unknown | 6 (2.3) | 7 (2.7) | 0.53 |
Data are no. (%) or mean ± SD and were compared with the χ2 test or the independent-sample t test, respectively. Boldface type indicates statistical significance. CTEPH: chronic thromboembolic pulmonary hypertension; NA: not applicable; BMI: body mass index; WHO: World Health Organization; COPD: chronic obstructive pulmonary disease.