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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Nat Genet. 2015 May 11;47(6):582–588. doi: 10.1038/ng.3303

Figure 4. Combined risk model for SNVs and CNVs: inherited and de novo.

Figure 4

Integrative risk model for ASD, based on de novo and inherited events, and covering both SNVs and CNVs. The model used is a stratified logistic regression model, which utilizes proband-sibling pairs to estimate the odds ratio (i.e., risk of ASD) for each type of event (see also Supplementary Table 7).