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. Author manuscript; available in PMC: 2015 May 29.
Published in final edited form as: Pac Symp Biocomput. 2013:212–223.

Fig. 5.

Fig. 5

(a) Effect of incorporation of prior information on the GO significance of the obtained clusters. β controls the degree of enforcement of the KEGG prior knowledge (b) A sunburst diagram for the BRCA dataset. In this alternative representation of the ReKS clustering results, each concentric circle represents a level of the tree. Each ring is sub-divided into clusters. The color of a leaf node denotes the GO significance of the cluster. There exists a small anti-correlation (ρ = -0.2112, p < 10-7) between the level from which a cluster splits off, and its GO significance (c) A part of the tree enriched with genes implicated for breast cancer (level 2 and down), and the GO significance and categories of the 169 gene super-cluster (grey box).