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Features of Angelman syndrome
| Consistent (100%) | Frequent (80%) | Associated (20–80%) |
|---|---|---|
| Developmental delay | Seizures | Hypotonia |
| Ataxia and/or tremors | Microcephaly | Strabismus |
| Absent speech | Frequent drooling, mouthing behaviors | |
| Happy demeanor: including hand flapping, frequent laughter/smiling | Protruding tongue, tongue thrusting | |
| Wide mouth, wide spaced teeth Sleep disturbances | ||
| Sleep disturbances | ||
| Fascination with water | ||
| Anxiety |
