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. 2015 Feb 15;5(3):1000–1016.

Figure 2.

Figure 2

HM910 significantly inhibited tumor growth in vivo. Antitumor effects of HM910 in a NCI-H929 xenograft model in athymic nude mice. A & B. Tumor size. The picture was taken on the 11th day after implantation. The various treatments were as follows: (a) saline (q4d × 2); (b) topotecan (2 or 4 mg/kg, i.p., q4d × 2); (c) HM910 (35 mg/kg, i.p., q4d × 2); (d) HM910 (25 mg/kg, i.p., q4d × 2); and (e) HM910 (18 mg/kg, i.p., q4d × 2). C & D. Changes in tumor volume with time after tumor cell inoculation. Points, mean tumor volume for each group of 8 mice after implantation; bars, SEM. E & F. Changes in weight with time after tumor cell inoculation.