Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A schematic model illustrating the possible pathway targeting NCI-H929 cell by HM910. HM910 induced apoptosis via the activation of mitochondrial-dependent apoptotic pathway. More importantly, HM910 induced cell cycle arrest in G1 phase via downregulating the expressions of CDK4 and 6, resulting in down-regulation of cyclin D1.
