Figure 3.

Serologic level of Wnt2 determined by ELISA experiments in patients with NSCLC and healthy volunteers. A: Serum Wnt2 levels of patients with NSCLC (patients were divided into ADC and non-ADC groups) and healthy controls. Black line indicates the cutoff value (4.39 ng/ml) which was determined by ROC curve in MedCalc programme. B: Distribution of Wnt2 IHC staining results of 67 NSCLC patients according to serum Wnt2 level. C: Serum levels of Wnt2 before and after radical resection of primary tumors in 12 NSCLC patients (P = 0.001). Black lines indicate cutoff values. D: ROC curve analysis of serum Wnt2 (Red line) and CEA (green line) as serum markers for adenocarcinoma of lung cancer. x-axis: 1-Specificity; y-axis, sensitivity. *: P < 0.05.