Table 2.

Cox’s proportional hazards model analysis of prognostic factors in patients with NSCLCs

Variables	Unfavorable/favorable	Overall survival (OS)		Relapse free survival (RFS)
		HR (95% CI)	P value	HR (95% CI)	P value
Univariate analysis
WNT2	Strong (+)/weak (+)or (-)	1.485 (1.080-2.042)	0.015	1.618 (1.198-2.185)	0.002
Gender	Female/male	0.732 (0.803-1.366)	0.732	0.990 (0.765-1.280)	0.937
Age	≥ 65/< 65	0.935 (0.706-1.239)	0.642	0.870 (0.663-1.140)	0.312
Pathologic type	Non-ADC/ADC	1.250 (0.933-1.675)	0.012	1.321 (1.001-1.742)	0.049
pT stage	(T3+T4)/(T1+T2)	3.160 (2.108-4.737)	< 0.0001	2.320 (1.596-3.373)	< 0.0001
pN stage	(N1+N2)/N0	3.437 (2.154-5.486)	< 0.0001	3.025 (1.950-4.692)	< 0.0001
Differentiation	Poor/(moderate+well)	1.594 (1.208-2.103)	0.001	1.341 (1.028-1.750)	0.031
Multivariate analysis
WNT2	Strong (+)/weak (+) or (-)	1.319 (1.001-1.739)	0.049	1.589 (1.180-2.141)	0.002
pT stage	(T3+T4)/(T1+T2)	3.351 (2.273-4.939)	< 0.0001	2.302 (1.584-3.346)	< 0.0001
pN stage	(N1+N2)/N0	3.446 (2.183-5.442)	< 0.0001	2.960 (1.912-4.582)	< 0.0001
Differentiation	Poor/(moderate+well)	1.582 (1.211-2.066)	0.001	1.316 (1.012-1.712)	0.040
Pathologic type	Non-ADC/ADC	1.310 (0.995-1.726)	0.055	-	-