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. 2015 Feb 15;5(3):1124–1132.

Figure 1.

Figure 1

LEF1 has a positive correlation with has-miR-181a. A. A clustering analysis between paired miRNA expression comparison of LNCaP-AI/LNCaP and LNCaP-AI/LNCaP-AI-LEF1shRNA, top 9 up-regulated miRNAs were listed. B. LEF1 expression level in five (LNCaP, LNCaP-AI, C4-2B, DU-145 and PC-3) PCa cell lines and two benign prostate cell lines (RC-170, RC-165). C and D. LEF1 and miR-181a expression in LNCaP cells. LEF1 plasmid transfection increased miR-181a in LNCaP cells. E and F. miR-181a expression decreased with LEF1 knockdown by shRNA in LNCaP-AI cells. GAPDH and U6 were used for normalization.