Table 3.
Copy number of mtDNA in gliomas: univariate associations with clinicopathological characteristics
| Characteristics | Copy number | P |
|---|---|---|
|
| ||
| OR* (95% CI) | ||
| Male vs. Female | 0.87 (0.55-1.38) | 0.55 |
| Age1 | 0.83 (0.67-1.04) | 0.11 |
| WHO grade2 | 0.34 (0.16-0.73) | 0.006 |
| Pathological diagnosis3 | 0.71 (0.47-1.07) | 0.10 |
| Recurrence | 0.40 (0.17-0.96) | 0.04 |
| Smoking history | 0.92 (0.42-2.02) | 0.84 |
| Seizures | 2.21 (1.07-4.54) | 0.03 |
| KPS4 | 1.73 (0.83-3.59) | 0.14 |
| Survival status5 | 0.36 (0.17-0.76) | 0.007 |
OR: odds ratio with 95% confidence interval (CI);
Age (per 10 years);
Tumor grade (I/II; III/IV);
Pathological diagnosis (DA; OL; AOA; GBM; EP);
KPS (≤ 80; > 80);
Survival status (Alive vs. Dead).