Table 5.

Stratified analyses of the associations between WT1 genotypes and breast cancer risk by age of 50 years

SNPs	Genetic model	Genotype	≤ 50 years				> 50 years
			Controls (n = 556)	Cases (n = 460)	adjusted ORa	P	Controls (n = 193)	Cases (n = 249)	adjusted ORa	P
rs16754	Codominant	GG	283	249	reference		101	129	reference
		GA	218	180	0.9430 (0.7240-1.2290)	0.6652	75	105	1.1240 (0.7490-1.6890)	0.5718
		AA	55	31	0.5960 (0.3690-0.9620)	0.0340	17	15	0.7960 (0.3710-1.7090)	0.5584
	Dominant	GG	283	249	reference		101	129	reference
		GA + AA	273	211	0.8710 (0.6780-1.1200)	0.2813	92	120	1.0670 (0.7230-1.5730)	0.7450
	Recessive	GG + GA	501	429	reference		176	234	reference
		AA	55	31	0.6110 (0.3840-0.9730)	0.0378	17	15	0.7560 (0.3600-1.5880)	0.4597
	Allele contrast	G	784	678	reference		277	363	reference
		A	328	242	0.8370 (0.6860-1.0200)	0.0778	109	135	0.9920 (0.7300-1.3480)	0.9607
rs3930513	Codominant	TT	301	266	reference		105	139	reference
		TG	211	168	0.9060 (0.6950-1.1810)	0.4660	73	95	1.0290 (0.6830-1.5490)	0.8921
		GG	44	26	0.6240 (0.3710-1.0500)	0.0759	15	15	0.8810 (0.4030-1.9270)	0.7512
	Dominant	TT	301	266	reference		105	105	reference
		TG + GG	255	194	0.8560 (0.6650-1.1020)	0.2283	88	110	1.0050 (0.6800-1.4840)	0.9811
	Recessive	TT + TG	512	434	reference		178	234	reference
		GG	44	26	0.6500 (0.3900 -1.0810)	0.0967	15	15	0.8710 (0.4060-1.8690)	0.7225
	Allele contrast	T	813	700	reference		283	373	reference
		G	299	220	0.8420 (0.6860-1.0320)	0.0979	103	125	0.9800 (0.7170-1.3400)	0.8994
rs5030141	Codominant	AA	263	239	reference		92	125	reference
		AC	232	178	0.8540 (0.6540-1.1140)	0.2437	81	103	0.9870 (0.6550-1.4850)	0.9483
		CC	61	43	0.7690 (0.4990-1.1870)	0.2359	20	21	0.8440 (0.4230-1.6840)	0.6297
	Dominant	AA	263	239	reference		92	125	reference
		AC + CC	293	221	0.8360 (0.6510-1.0740)	0.1615	101	124	0.9590 (0.6500-1.4140)	0.8318
	Recessive	AA + AC	495	417	reference		173	228	reference
		CC	61	43	0.8260 (0.5440-1.2530)	0.3684	20	21	0.8490 (0.4370-1.6500)	0.6291
	Allele contrast	A	758	656	reference		265	353	reference
		C	354	264	0.8630 (0.7110-1.0470)	0.1349	121	145	0.9440 (0.7010-1.2720)	0.7044
rs5030317	Codominant	CC	296	260	reference		104	134	reference
		CG	209	173	0.9390 (0.7200-1.2240)	0.6410	74	102	1.1150 (0.7430-1.6730)	0.6000
		GG	51	27	0.5510 (0.3330-0.9120)	0.0204	15	13	0.7520 (0.3340-1.6900)	0.4899
	Dominant	CC	296	260	reference		104	134	reference
		CG + GG	260	200	0.8600 (0.6690-1.1070)	0.2428	89	115	1.0560 (0.7150-1.5580)	0.7854
	Recessive	CC + CG	505	433	reference		178	236	reference
		GG	51	27	0.5660 (0.3460-0.9250)	0.0231	15	13	0.7170 (0.3250-1.5830)	0.4106
	Allele contrast	C	801	693	reference		282	370	reference
		G	311	227	0.8210 (0.6710-1.0050)	0.0560	104	128	0.9830 (0.7200-1.3420)	0.9148
rs5030320	Codominant	GG	297	261	reference		104	134	reference
		GA	207	172	0.9420 (0.7220-1.2280)	0.6571	74	102	1.1150 (0.7430-1.6730)	0.6000
		AA	52	27	0.5440 (0.3290-0.8980)	0.0173	15	13	0.7520 (0.3340-1.6900)	0.4899
	Dominant	GG	297	261	reference		104	134	reference
		GA + AA	259	199	0.8600 (0.6680-1.1060)	0.2397	89	115	1.0560 (0.7150-1.5580)	0.7854
	Recessive	GG + GA	504	433	reference		178	236	reference
		AA	52	27	0.5570 (0.3420-0.9090)	0.0193	15	13	0.7170 (0.3250-1.5830)	0.4106
	Allele contrast	G	801	694	reference		282	370	reference
		A	311	226	0.8180 (0.6680-1.0010)	0.0508	104	128	0.9830 (0.7200-1.3420)	0.9148

^aadjusted by age (continuous variable) and menopausal status.