Table 6.

Stratified analyses of the associations between WT1 genotypes and breast cancer risk by menopausal status

SNPs	Genetic model	Genotype	Pre-menopause				Post-menopause
			Controls (n = 519)	Cases (n = 447)	adjusted ORa	P	Controls (n =2 30)	Cases (n = 262)	adjusted ORa	P
rs16754	Codominant	GG	262	236	reference		122	142	reference
		GA	203	182	0.9890 (0.7520-1.3010)	0.9387	90	103	0.9750 (0.6710-1.4180)	0.8955
		AA	54	29	0.5400 (0.3290-0.8860)	0.0148	18	17	0.8410 (0.4140-1.7100)	0.6329
	Dominant	GG	262	236	reference		122	142	reference
		GA + AA	257	211	0.8900 (0.6860-1.1550)	0.3817	108	120	0.9530 (0.6670-1.3630)	0.7927
	Recessive	GG + GA	465	418	reference		212	245	reference
		AA	54	29	0.5420 (0.3350-0.8780)	0.0127	18	17	0.8500 (0.4260-1.6980)	0.6456
	Allele contrast	G	727	654	reference		334	387	reference
		A	311	240	0.8290 (0.6760-1.0170)	0.0727	126	137	0.9440 (0.7100-1.2540)	0.6903
rs3930513	Codominant	TT	277	255	reference		129	150	reference
		TG	198	168	0.9180 (0.6980-1.2080)	0.5418	86	95	0.9470 (0.6500-1.3810)	0.7782
		GG	44	24	0.5350 (0.3120-0.9180)	0.0232	15	17	1.0100 (0.4840-2.1120)	0.9779
	Dominant	TT	277	255	reference		129	150	reference
		TG + GG	242	192	0.8450 (0.6510-1.0980)	0.2082	101	112	0.9560 (0.6680-1.3700)	0.8084
	Recessive	TT + TG	475	423	reference		215	245	reference
		GG	44	24	0.5540 (0.3270-0.9400)	0.0284	15	17	1.0320 (0.5010-2.1250)	0.9313
	Allele contrast	T	752	678	reference		344	395	reference
		G	286	216	0.8130 (0.6590-1.0040)	0.0544	116	129	0.9760 (0.7300-1.3060)	0.8717
rs5030141	Codominant	AA	243	231	reference		112	133	reference
		AC	216	176	0.8730 (0.6630-1.1500)	0.3344	97	105	0.9010 (0.6190-1.3130)	0.5886
		CC	60	40	0.6920 (0.4410-1.0860)	0.1096	21	24	0.9800 (0.5160-1.8610)	0.9497
	Dominant	AA	243	231	reference		112	133	reference
		AC + CC	276	216	0.8330 (0.6420-1.0810)	0.1689	118	129	0.9150 (0.6410-1.3070)	0.6263
	Recessive	AA + AC	459	407	reference		209	238	reference
		CC	60	40	0.7360 (0.4770-1.1350)	0.1653	21	24	1.0270 (0.5530-1.906)	0.9337
	Allele contrast	A	702	638	reference		321	371	reference
		C	336	256	0.8400 (0.6880-1.0260)	0.0881	139	153	0.9530 (0.7240-1.2560)	0.7342
rs5030317	Codominant	CC	275	247	reference		125	147	reference
		CG	194	174	0.9830 (0.7470-1.2950)	0.9056	89	101	0.9630 (0.6630-1.4000)	0.8435
		GG	50	26	0.5170 (0.3090-0.8660)	0.0123	16	14	0.7570 (0.3540-1.6170)	0.4717
	Dominant	CC	275	247	reference		125	147	reference
		CG + GG	244	200	0.8830 (0.6800-1.1470)	0.3517	105	115	0.9320 (0.6510-1.3330)	0.6991
	Recessive	CC + CG	469	421	reference		214	248	reference
		GG	50	26	0.5080 (0.3040-0.8500)	0.0110	16	14	0.7680 (0.3650-1.6160)	0.4876
	Allele contrast	C	744	668	reference		339	395	reference
		G	294	226	0.8220 (0.6670-1.0120)	0.0645	121	129	0.9180 (0.6870-1.2250)	0.5600
rs5030320	Codominant	GG	275	248	reference		126	147	reference
		GA	193	173	0.9760 (0.7410-1.2860)	0.8644	88	101	0.9800 (0.6740-1.4240)	0.9139
		AA	51	26	0.5080 (0.3040-0.8500)	0.0099	16	14	0.7620 (0.3570-1.6280)	0.4829
	Dominant	GG	275	248	reference		126	147	reference
		GA + AA	244	199	0.8740 (0.6730-1.1350)	0.3135	104	115	0.9460 (0.6610-1.3540)	0.7628
	Recessive	GG + GA	468	421	reference		214	248	reference
		AA	51	26	0.5130 (0.3110-0.8480)	0.0092	16	14	0.7680 (0.3650-1.6160)	0.4876
	Allele contrast	G	743	669	reference		340	395	reference
		A	295	225	0.8130 (0.6600-1.0020)	0.0520	120	129	0.9270 (0.6940-1.2380)	0.6066

^aadjusted by age (continuous variable) and menopausal status.