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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Gastroenterol Clin North Am. 2015 Apr 9;44(2):203–231. doi: 10.1016/j.gtc.2015.02.001

Table 4.

Prospective and Registry-based cohort studies reporting progression risk in LGD, since 2000

AUTHOR(S) YEAR SETTING STUDY
DESIGN
BE
PATIENTS
FOLLOWED
MALE INCIDENCE OF
EAC, %
PER
YEAR, IN
NDBE
INCIDENCE OF
EAC OR
HGD, %
PER
YEAR, IN
NDBE
INCIDENCE OF
EAC, %
PER
YEAR, IN
LGD
INCIDENCE OF
EAC OR
HGD, %
PER
YEAR, IN
LGD
THOTA ET AL141 2014 U.S. Prospective
Cohort
299 79.0 NR NR 0.80% 3.10%
PICARDO ET AL132 2014 U.K. Prospective
Cohort
1093 67.1 0.13% 0.72% 1.98% 6.49%
DUITS ET AL140 2014 Netherlands Retrospective
Cohort
293 76.0 NR 0.60% NR 9.10%
RUGGE ET AL131 2012 Italy Prospective
Cohort
841 77.0 NR 0.53% NR 3.17%
HVID-JENSEN ET AL10 2011 Netherlands Prospective
Cohort
11028 66.8 0.09% 0.25% 0.55% 1.67%
BHAT ET AL11 2011 U.K. Retrospective
Cohort
8522 57.9 0.10% 0.15% 0.92% 1.31%
WANI ET AL107 2011 U.S. Prospective
Cohort
1755 85.0 NR NR 0.44% 1.83%
SCHOUTEN ET AL139 2011 Netherlands Retrospective
Cohort
605 54.0 0.30% NR 0.41% NR
DE HOED ET AL130 2011 Netherlands Prospective
Cohort
133 54.9 NR 0.35% NR 1.62%
JUNG ET AL138 2011 U.S. Retrospective
Cohort
355 72.0 0.25$ 0.66% 0.23% 0.71%
DE JONGE ET AL122 2010 Netherlands Retrospective
Cohort
42207 62.5 0.39% 0.51% 0.77% 1.06%
CURVERS ET AL137 2010 Netherlands Retrospective
Cohort
1198 67.0 NR 0.49% 0.34% 13.40%
WONG ET AL136 2010 U.S. Retrospective
Cohort
248 NR 0.51% 0.61% 1.51% 1.51%
GATENBY ET AL121 2009 U.K. Retrospective
Cohort
146 NR NR NR 2.70% 4.60%
ALCEDO ET AL135 2009 Spain Retrospective
Cohort
386 79.0 0.52% 0.95% 0.00% 0.00%
SWIZER-TAYLOR ET AL129 2008 U.K. Retrospective
Cohort
212 69.0 0.68% 0.85% 0.75% 3.16%
LIM ET AL128 2007 U.K. Retrospective
Cohort
357 57.7 NR 0.62% NR 3.30%
VIETH EL AL134 2006 Germany Retrospective
Cohort
748 67.8 0.23% 0.23% 4.67% 4.67%
DULAI ET AL127 2005 U.S. Retrospective
Cohort
575 99.0 0.09% 0.36% 36.00% 1.28%
CONIO ET AL126 2003 Italy Prospective
Cohort
166 81.3 0.36% 0.61% 2.27% 3.44%
SCHNELL ET AL133 2001 U.S. Retrospective
Cohort
1099 NR NR NR 0.19% NR
WESTON ET AL114 2001 U.S. Prospective
Cohort
48 100.0 NR NR 0.61% 2.43%
REID ET AL108 2000 U.S. Prospective
Cohort
327 NR 1.05% NR 1.50% NR
SKACEL ET AL113 2000 U.S. Retrospective
Cohort
25 84.0 NR NR 0.15% 0.52%

Data from Refs 10,11,107,108,113,114,121,122,126134141.