Table 1.
Inclusion criteria | Exclusion criteria |
---|---|
Age between 18 and 70 | Diabetes mellitus |
Chronic kidney disease stage IV-V (eGFR <30 ml/min/1.73m2) | |
History of transplantation | |
History of acute kidney injury before randomization | |
Active infection | |
Cancer patients treated with intravenous cisplatin | Use of other nephrotoxic agents such as nonsteroidal anti-inflammatory drugs, aminoglycosides, colistin, vancomycin, cyclosporine, tacrolimus |
Receiving contrast media during last 72 h | |
Liver disease (bilirubin >2 mg/dl, transaminase levels >2.5 times the upper limit normal) | |
Written consent | Patients with high risks of dehydration owing to poor oral intake |
High blood pressure (>180/110 mmHg despite antihypertensive medications) | |
Hypersensitivity to gemigliptin or its excipients | |
Low compliance to gemigliptin treatment |
Abbreviation: eGFR estimated glomerular filtration rate