Table 1.
Baseline characteristics
| All Children | Presence of LGE | |||
|---|---|---|---|---|
| Variable | (n = 40) | Yes (n = 10) | No (n = 30) | p Value |
| Age (years) | 13.7 ± 3.3 | 14.0 ± 2.1 | 13.6 ± 3.6 | 0.753 |
| Male, n (%) | 29 (73) | 9 (90) | 20 (67) | 0.233 |
| Family history of LVNC, n (%) | 3 (8) | 1 (10) | 2 (7) | 1.000 |
| Symptoms | ||||
| Dyspnoea, n (%) | 21 (53) | 9 (90) | 12 (40) | 0.004 |
| Chest pain, n (%) | 2 (5) | 0 | 2 (7) | 1.000 |
| Syncope/pre-syncope, n (%) | 7 (18) | 1 (10) | 6 (20) | 0.651 |
| Thrombo-embolic events, n (%) | 0 | 0 | 0 | |
| NYHA functional class | 2.4 ± 1.0 | 3.0 ± 0.9 | 2.1 ± 0.9 | 0.016 |
| I, n (%) | 10 (25) | 1 (9) | 9 (30) | |
| II, n (%) | 11 (28) | 1 (9) | 10 (33) | |
| III, n (%) | 14 (35) | 5 (55) | 9 (30) | |
| IV, n (%) | 5 (12) | 3 (27) | 2 (7) | |
| Abnormal ECG, n (%) | 36 (90) | 10 (100) | 26 (87) | 0.559 |
| VT/VF, n (%) | 7 (18) | 3 (30) | 4 (13) | 0.361 |
| Medications | ||||
| β-Blockers, n (%) | 29 (73) | 8 (80) | 21 (70) | 0.694 |
| ACEI/ARB, n (%) | 29 (73) | 10 (100) | 19 (63) | 0.020 |
| Aldosterone antagonists, n (%) | 27 (68) | 10 (100) | 17 (57) | 0.008 |
| Loop diuretics, n (%) | 22 (55) | 9 (90) | 13 (43) | 0.011 |
| Amiodarone, n (%) | 2 (5) | 2 (20) | 0 | 0.067 |
Values are mean ± SD or n (%)