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. 2015 May 10;10:59. doi: 10.1186/s13023-015-0261-6

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© Regnault et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Conceptual model of the impact of phenylketonuria (PKU) and its treatment on patients and their parents. From the patients’ perspective, PKU can have an impact on health status, psychological function, family life and social function. PKU treatment was also reported as having either a negative impact or no impact (patients who indicated that they did not know any other way of living and had coped with their disease).