Table 7.
Study | Total No. of CVS sample | No. of CVS samples with trisomy 2 | Prevalence of trisomy 2 in CV | No. of TFM with trisomy 2 after a mosaic in CV | No. of cases with UPD investigation | No. of UPD2 retrieved | Incidence of UPD in mosaic trisomy 2 in CV (%) | |
---|---|---|---|---|---|---|---|---|
% | 1/x | |||||||
Wolstenholme, 1996 | 66,129 | 41 | 0.06 | 1613 | na | na | na | na |
Hahnemann and Vejerslev, 1997 | 92,246 | 11 | 0.01 | 8386 | 0 | na | na | na |
Sago et al., 1997 | 10,500 | 11 | 0.10 | 955 | na | 11 | 0 | 0 |
Sifakis et al., 2010 | 37,474 | 45 | 0.12 | 833 | 0 | 43 | 0 | 0 |
Present Study * | 52,673 | 74 | 0.14 | 712 | 0 | 62 | 0 | 0 |
Total | 259,022 | 182 | 0.07 | 1423 | 0 | 116 | 0 | 0 |
* Including cases published in Grati et al., 2006; na = not available.