Table 1.
Mechanical Testing Results of Collagen-Coated, Electrospun Polycaprolactone Grafts as Compared to Native Rat Anterior Cruciate Ligament
| Group | Stiffness (N/mm) | Peak load (N) |
|---|---|---|
| Col graft, immediately postimplantation | 6.2±3.9 | 7.7±3.0 |
| Col graft, 16 weeks | 12.4±3.8a | 16.0±3.4a |
| Col+bFGF graft, 16 weeks | 23.3±8.1a | 23.1±6.1a |
| Col+HFF graft, 16 weeks | 4.4±1.2 | 17.0±6.9a |
| Col+HFF+bFGF graft, 16 weeks | 10.1±2.1a | 15.1±4.9a |
| Native ACL | 39.6±6.7b | 56.7±1.6b |
a
Significantly higher than Col graft immediately postimplatation.
b
Significantly higher than all other groups, n=5, p<0.05.
ACL, anterior cruciate ligament; bFGF, basic fibroblast growth factor; Col, collagen coating; HFF, human foreskin fibroblast.